منابع مشابه
Opioid analgesics increase incidence of somnolence and dizziness as adverse effects of pregabalin: a retrospective study
BACKGROUND Pregabalin, a gabapentinoid, is an adjuvant analgesic for treatment of neuropathic pain, but it has serious adverse effects such as somnolence and dizziness, particularly in elderly patients. Although decreased renal function is considered to the contributing factor for high frequency of these adverse effects in elder patients, only a few systematic clinical investigations, especiall...
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The clycoxygenase (COX) enzyme forms locally active prostaglandins responsible for producing inflammation and pain. Classical non-steroidal anti-inflammatory drugs (NSAID) inhibit the COX-2 enzyme that produces inflammatory prostaglandins as well as the COX-1 enzyme that produces gastric mucosa protecting prostaglandins. By specifically inhibiting only the COX-2 enzyme, coxibs thus reduce pain ...
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ژورنال
عنوان ژورنال: Acta Scientific Orthopaedics
سال: 2019
ISSN: 2581-8635
DOI: 10.31080/asor.2019.02.0089